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A pituitary tumor is an abnormal growth in the pituitary gland. The pituitary is a small gland in the brain. It is located at the base of the brain, behind the back of the nose. It makes hormones that affect many other glands and many functions in your body. Most pituitary tumors are benign (not cancer). They don't spread to other parts of your body. But they can cause the pituitary to make too few or too many hormones, causing problems in the body.
Pituitary tumors that make too many hormones will often cause other glands to make more hormones. That will cause symptoms linked to each of the specific hormones. Many pituitary tumors will also press against the nearby optic nerves. This can cause vision problems. Other pituitary tumors may cause double vision by pressing on the nerves to the muscles that move the eyes. Others may bleed, leading to severe headache. This is known as apoplexy.
Most pituitary tumors don't cause symptoms. So they are not diagnosed. Or they are found only during routine brain imaging or blood tests. About 1 in 4 people may have small pituitary tumors without knowing it.
Below are the main types of benign pituitary tumors.
These tumors are the most common type. They don't make extra hormones. You may not have any symptoms until the tumor grows to a certain size. When the tumor is big enough, it may cause headaches and vision problems. Large pituitary tumors can put pressure on normal pituitary cells. This leads to symptoms caused by decreased hormone production.
These benign tumors are also common. They make too much prolactin. If you're biologically female, high prolactin levels can make your menstrual period irregular, or even stop your period. These tumors can also cause you to make breast milk, even if you are not pregnant or nursing. If you're biologically male, you may have erectile dysfunction or a lack of interest in sex. You may also have enlarged breasts, a low sperm count, decreased bone density or less body hair. In time, you may have headaches and vision problems, such as double vision.
These tumors make too much ACTH (adrenocorticotropic hormone). This hormone stimulates the adrenal gland to make steroids that affect metabolism. These are called glucocorticoids (cortisol). They reduce redness and swelling (inflammation) all over the body. They also slow down your immune system. Too much ACTH can cause Cushing's disease. This disease causes fat buildup in your face, neck, back, belly (abdomen), and chest. Also your arms and legs tend to become thin. You may also have purple stretch marks, bruises, and high blood pressure. These tumors can also weaken your bones. Additionally, it can cause diabetes and hypertension.
These tumors make too much growth hormone. In children, too much growth hormone stimulates the growth of almost all the bones in the body. When that occurs, the result is called gigantism. Gigantism can include increased height (over 7 feet), very quick growth, joint pain, and heavy sweating. In adults, too much growth hormone causes a condition called acromegaly. It may include:
Experts don't know what causes these tumors. But some syndrome conditions, such as multiple endocrine neoplasia type I (MEN 1) may raise your risk. This condition is passed down through families (inherited).
Symptoms depend on the type of tumor and the area of the pituitary gland that is affected. These tumors can lead to symptoms caused by too much or too little of the pituitary hormones. Each person's symptoms may vary.
The symptoms may also look like other health problems. Always see your doctor for a diagnosis.
Your doctor will ask about your health history and do a physical exam. You may also need one or more of these tests:
Treatment will depend on your symptoms, age, and general health. It will also depend on how severe the condition is.
Treatment may include:
Contact your doctor if your symptoms return or you have new symptoms.
Tips to help you get the most from a visit to your doctor: